Non-Alcoholic Fatty Liver Disease: A 360-degree Overview

Introduction.- Obesity and NAFLD: same problem? The burden of NAFLD worldwide.- Histo-pathology of NAFLD.- NAFLD and insulin resistance: a multisystemic.- Etiopathogenesis of NAFLD: diet, gut and NASH.- Etiopathogenesis of NAFLD: molecular mechanisms of fibrogenesis.- The natural history of NAFLD: Environmental vs Genetic Risk Factors.- NAFLD and endocrine disease: clinical implications.- NAFLD and Cardiovascular Disease: clinical implications.- NAFLD, Hepatocellular Carcinoma and extrahepatic cancers.- NAFLD in children: implications for the future.- Diagnostic algorithm for the identification of NAFLD in primary care.- Non-Invasive diagnostic approach to NASH: Biological Markers.- Non-Invasive diagnostic approach to NASH: Radiological Diagnostics.- Dietary approach to NAFLD.- Physical Activity in NAFLD: what and how much? Pharmacological Therapy of NASH.- Bariatric Surgery and NASH: a feasible option? Liver transplantation and NASH.- Unmet needs and future goals.