Triple Helix Forming Oligonucleotides

Foreword. Section I: Background and Structural Aspects. 1. The Antigene Strategy: Progress and Perspectives in Selective Gene Silencing; C. Hélène. 2. Triple-Helix Structure. The Triple-Helix-Forming Oligonucleotide; H. Porumb. 3. Thermodynamic State Diagrams of Oligonucleotide Triple Helices; G.E. Plum, K.J. Breslauer. 4. Imaging of Triplexes by Electron and Scanning Force Microscopy; D. Cherny. 5. Chemical Modifications of Triple Helix Forming Oligonucleotides; U. Asseline. 6. Triple Helix Formation with Modified Oligonucleotides; S.M. Gryaznov. 7. Oligonucleotides as Artificial DNases; V. Zarytova, A. Levina. Section II: The Biology of Triple Helices. 8. Potential Mechanisms of Action; L.J. Maher. 9. Oligonucleotide Uptake and Delivery in Tissue Culture Cells; S.W. Ebbinghaus, et al. 10. Triple-Stranded Complexes as Antigene Molecules: Transcription Inhibition Ex Vivo; C. Giovannangeli. 11. Gene-Targeting Triple Helix Forming Purine Oligonucleotides; F. Svinarchuk, C. Malvy. 12. DNA Triple Helix as a Tool to Regulate Cytokine Gene Expression; M. Kochetkova, M.F. Shannon. 13. Genome Modification by Triplex-Forming Oligonucleotides; K.M. Vasquez, P.M. Glazer. 14. Psoralen-Coupled Oligonucleotides: In Vivo Binding and Repair; F.-X. Barre, et al. 15. Structure and Biology of H DNA; S.M. Mirkin. 16. Triplex-Binding Proteins; A.-L. Guieysse, D. Praseuth. 17. RNA and Triple Helices; Kyonggeun Yoon, etal. Section III: New Developments and Applications. 18. Triplexes Involving PNA; T. Bentin, P.E. Nielsen. 19. Triple Helix Stabilizing Agents; C. Escudé, T. Garestier. 20. New Targets for Triple Helix Forming Oligonucleotides; J.S. Sun. 21. Triplexes and Biotechnology; M.D. Frank-Kamenetskii. Index.