Hormones and Cancer

I: Underlying Mechanisms and Principles.- 1. Neoplastic Transformation: Oncogenes, Tumor Suppressors, Cyclins, and Cyclin-Dependent Kinases.- 2. TGF-? Inhibition of Intestinal Epithelial Cell Proliferation: G1 Cyclins, Cyclin Dependent Kinases, and Cyclin Kinase Inhibitors.- 3. RET Proto-Oncogene and Its Role in Multiple Endocrine Neoplasia and Medullary Thyroid Cancer.- 4. The Nuclear Hormone Receptor Superfamily: Structure and Function.- 5. Retinoids: Concepts for Separation of Desirable and Undesirable Effects in the Treatment or Prevention of Cancer.- II: Breast Cancer.- 6. Clinical Aspects of Breast Cancer.- 7. The Genetics of Breast Cancer.- 8. Growth Factors and Modulation of Endocrine Response in Breast Cancer.- 9. Role of Altered Estrogen Receptors in Breast Cancer.- 10. Progestins, Progesterone Receptors, and Breast Cancer.- 11. Molecular, Cellular, and Systemic Mechanisms of Antiestrogen Action.- 12. Aromatase Inhibitors and Breast Cancer.- III: Prostate Cancer.- 13. Current Concepts in the Treatment of Cancer of the Prostate.- 14. Tumor Suppressor Genes and Oncogenes in Human Prostate Cancer.- 15. Prostatic Growth Factors, Cancer, and Steroid Hormone Activity.- 16. Androgen Receptors in Human Prostate Cancer: Heterogeneous Expression, Gene Mutations, and Polymorphic Variants.- IV: Hematological Malignancies.- 17. Basic and Clinical Studies of Glucocorticosteroid Receptors in Lymphoid Malignancies.- 18. Glucocorticoid Actions on Normal and Neoplastic Lymphocytes: Activation of Apoptosis.- 19. Clinical Aspects of Acute Promyelocytic Leukemia and Response to Retinoid Therapy.- 20. Molecular Biology of Acute Promyelocytic Leukemia.- Keyword Index.