Nutrients in Cancer Prevention and Treatment

Part I. Carcinogenesis. G Protein Pathways and Regulation of Neoplastic Transformation. Part II. Cancer Prevention Studies: Lab Studies. Vitamin E Succinate Inhibits Protein Kinase C: Correlation with Its Unique Inhibitory Effects on Cell Growth and Transformation. Vitamin E Succinate: Mechanisms of Action as Tumor Cell Growth Inhibitor. Vitamin D, Gene Expression, and Cancer. Mechanisms of Cancer Prevention: Effects of Protease Inhibitors on Proteases and Gene Expression. Antioxidants and Cancer Prevention In Vivo and In Vitro. Ascorbic Acid and Gastrointestinal Cancer. Biochemistry and Pharmacology of Retinoids in Relation to Chemoprevention of Cancer. Involvement of Retinoic Acid Nuclear Receptors in Transcriptional Regulation of Tissue Transglutaminase, the Gene Involved in Apoptosis. Mechanisms of Dietary Fat-Induced Colon Cancer Promotion. Calories and Exercise as Modifiers of Cancer Risk. Polcyclic Aromatic Hydrocarbon-DNA Adducts in Smokers and Their Relationship to Micronutrient Levels and Glutathione-S-Transferase M1 Genotype. Aspects of Commercial Deep-Fat Frying of Fallafel and Its Relation to Liver Tumor. Part III. Cancer Prevention Studies: Human Studies. Antioxidant Vitamins and Cancer: The Physicians' Health Study and Women's Health Study. Beta-Carotene and Antioxidant Nutrients in Oral Cancer Prevention. Nutritional Prevention Trials for Colorectal Neoplasia. Part IV. Cancer Treatment Studies: Lab Studies. Vitamins Induce Cell Differentiation, Growth Inhibition, and Enhance the Effect of Tumor Therapeutic Agents on Some Cancer Cells In Vitro. Molecular and Biochemical Control of Tumor Growth Following Treatment with Carotenoids or Tocopherols. Inhibition and Regression of Experimental Oral Cancer by Beta Carotene and Vitamin E: Emerging Concepts. Novel Approaches to the Prevention of Chemotherapy-Induced Alopecia. Part V. Cancer Treatment Studies: Human Studies. Role of Vitamin A and Its Derivatives in the Treatment of Human Cancer. Use of Vitaminsas Adjunct to Conventional Cancer Therapy. Orthomolecular Treatment of Cancer. Index.