Animal Models in Cardiovascular Research

1. General principles of animal selection and normal physiological values 2. Anesthesia, chemical restraint (sedation), and analgesia 3. Normal cardiovascular parameters 4. Measuring cardiac function 5. Measuring vascular function and ventricular/arterial coupling dynamics 6. Isolated heart preparations, problems and pitfalls 7. Cardiovascular effects anesthetics, sedatives and post-operative analgesic agents 8. Iatrogenic and naturally occurring animal models of valvular, infectious and arrhythmic cardiovascular disease 9. Iatrogenic models of ischemic heart disease 10. Iatrogenic, transgenic and naturally occurring models of cardiomyopathy and heart failure 11. Iatrogenic and transgenic models of hypertension 12. Iatrogenic and transgenic models of atherosclerotic disease 13. Animal models for the study of neurohumeral and central neural control of the cardiovascular system 14. Cardiovascular studies involving other specific genetic knockouts