Antiviral Drugs and Interferon: The Molecular Basis of Their Activity

Introduction: Current Trends in Research on Antiviral Drugs (a Review).- 1 Introduction: Current Trends in Research on Antiviral Drugs (a Review).- Antiherpes Simplex Virus Drugs.- 2 Antiviral Activity of Iodinated Pyrimidine Deoxyribonucleosides.- 3 Antiviral Properties of Aranucleosides: Metabolic Considerations.- 4 Herpes Simplex Virus Thymidine Kinase-Dependent Antiviral Agents.- 5 Acyclovir.- 6 BVDU ((E)-5-(2-Bromovinyl)-2'-deoxyuridine).- 7 (2'-Fluoro-5-iodo-1-?-D-arabinofuranosylcytosine) (FIAC): Synthesis and Mode of Anti-Herpesvirus Activity.- 8 Herpesvirus-Specified DNA Polymerase as the Target for Developing Selective Antiherpesvirus Agents.- 9 Phosphonoformate and Phosphonoacetate.- 10 Distamycin and Derivatives: the Pyrrole Amidine Antiviral Antibiotics.- 11 Clinical Insights into the Metabolism of Arabinosyl Adenine and Interferon as Derived by Microbiological Assays.- Drugs Inhibitory to Viral Reverse Transcriptase.- 12 Modulation of Retrovirus DNA Polymerase Activity by Polynucleotides and their Analogs.- Antipoxvirus Drug.- 13 Antipoxvirus Activity of Isatin-?-Thiosemicarbazone (IBT).- Drugs Affecting Synthesis or Processing of mRNA.- 14 Halogenated Ribofuranosylbenzimidazoles.- 15 Ribavirin.- Drugs Affecting RNA Viruses.- 16 Molecular Basis of Guanidine Action.- 17 Mechanism of Action of 2-(?-hydroxybenzyl)-benzimidazole (HBB).- 18 Multiple Actions of Amantadine Against Influenza Viruses.- Interferon.- 19 Polynucleotide Inducers of Interferon: Studies with poly(G)-poly(C).- 20 Interferon and Interferon-like Factors in Plants.- 21 The Interferon System in Man: Nature of the Interferon Molecules and Mode of Action.