G protein Signaling Mechanisms in the Retina

1. Introduction: G-protein Signaling in the Retina

Kirill A. Martemyanov and Alapakkam P. Sampath

Part One: Phototransduction in Rods and Cones

2. G-protein Deactivation Mechanisms in Vertebrate Phototransduction

Ching-Kang Chen and Hung-Ya Tu

3. Signaling by Rod and Cone Photoreceptors: Opsin Properties, G-protein Assembly and Mechanisms of Activation

Alexander V. Kolesnikov, Oleg G. Kisselev, and Vladimir J. Kefalov

4. G-protein-effector Coupling in the Vertebrate Phototransduction Cascade

Nikolai O. Artemyev

Part Two: Inner Retinal GPCR Signaling Pathways

5. Interdependence among Members of the mGluR6 G-protein Mediated Signalplex of Retinal Depolarizing Bipolar Cells

Ronald G. Gregg, Thomas A. Ray, Nazarul Hasan, Maureen A. McCall, and Neal S. Peachey

6. Mechanistic Basis for G-protein Function in ON Bipolar Cells

Noga Vardi and Anuradha Dhingra

7. Modulation of Trpm1 and the mGluR6 cascade in ON Bipolar Cells

Scott Nawy

8. The Role of Dopamine in Fine-tuning Cone- and Rod-driven Vision

Rolf Herrmann and Vadim Y. Arshavsky

9. Regulation of Electrical Synaptic Plasticity in the Retina by G-protein Coupled Receptors

Part Three: Signaling by Photosensitive Ganglion Cells

10. The Functional Properties of the G-protein-coupled Receptor melanopsin in Intrinsically Photosensitive Retinal Ganglion Cells

Samer Hattar and Alan C. Rupp