Sodium and Water Homeostasis: Comparative, Evolutionary and Genetic Models

Introduction.- ANG II and water balance in frogs.- Sex differences in ANGII hypertension.- Na-K-ATPase b subunit association with tight junction Drosophila tub size and tight junction function,- Na-K-ATPase in hypertension.- Endothelin regulation of ion transport in non-mammlian transporting epithelia.- Genetic models of Endothelin regulation of sodium transport.- miRNA and sodium and water balance in the developing zebrafish.- miRNA and sodiumand water balance in mammals.- Comparative and genetic models of WNK signaling in osmotic homeostasis.- Genetics of WNK signaling and disease in humans.- Comparative and evolutionary physiology of Water channels.- Genetic models resulting in urine concentrating defect.- Water balance in desert-adapted animals.0 Comparisons of nephron morphology and the urine concentrating mechanism.- Non-traditional models: the giraffe kidney.- Non-traditional models: insect tubule transport.- Circadian clock in ion transporters in insect vision.- Circadian clock, melatonin, and osmoregulation in fishes.