Biomedical Nanotechnology: Methods and Protocols

1. Biomedical Nanotechnology

Sarah J. Hurst

Part I: Using Nanomaterials in Sensing, Imaging, and Therapeutics

2. Multiplexed Detection of Oligonucleotides with Biobarcoded Gold Nanoparticle Probes

Jae-Seung Lee

3. Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance

Jered B. Haun, Tae-Jong Yoon, Hakho Lee, and Ralph Weissleder

4. Real-Time Quantum Dot Tracking of Single Proteins

Jerry C. Chang and Sandra J. Rosenthal

5. Titanium Dioxide Nanoparticles in Advanced Imaging and Nanotherapeutics

Tijana Rajh, Nada M. Dimitrijevic, and Elena A. Rozhkova

6. Surface Modification and Biomolecule Immobilization on Polymer Spheres for Biosensing Applications

Chris R. Taitt, Lisa C. Shriver-Lake, George P. Anderson, and Frances S. Ligler

7. Multivalent Conjugation of Peptides, Proteins, and DNA to Semiconductor Quantum Dots

Duane E. Prasuhn, Kimihiro Susumu, and Igor L. Medintz

8. A Single SnO₂ Nanowire-Based Microelectrode

Jun Zhou, Yaguang Wei, Qin Kuang, and Zhong Lin Wang

9. Biosensing Using Nanoelectromechanical Systems (NEMS)

Ashish Yeri and Di Gao

10. Nano "Fly Paper" Technology for the Capture of Circulating Tumor Cells

Shutao Wang, Gwen E. Owens, and Hsian-Rong Tseng

11. Polymeric Nanoparticles for Photodynamic Therapy

Yong-Eun Koo Lee and Raoul Kopelman

12. Hydrogel Templates for the Fabrication of Homogeneous Polymer Microparticles

Ghanashyam Acharya, Matthew McDermott, Soo Jung Shin, Haesun Park, and Kinam Park

13. Antibacterial Application of Engineered Bacteriophage Nanomedicines: Antibody-Targeted, Chloramphenicol Prodrug Loaded Bacteriophages for Inhibiting the Growth of Staphylococcus aureus Bacteria

Lilach Vaks and Itai Benhar

14. Viruses as Nanomaterials for Drug Delivery

Dustin Lockney, Stefan Franzen, and Steven Lommel

15. Applications of Carbon Nanotubes in Biomedical Studies

Hongwei Liao, Bhavna Paratala, Balaji Sitharaman, and Yuhuang Wang

16. Electrospun Nanofibrous Scaffolds for Engineering Soft Connective Tissues

Roshan James, Udaya S. Toti, Cato T. Laurencin, and Sangamesh G. Kumbar

17. Peptide Amphiphiles and Porous Biodegradable Scaffolds for Tissue Regeneration in the Brain and Spinal Cord

Rutledge G. Ellis-Behnke and Gerald E. Schneider

18. Computational Simulations of the Interaction of Lipid Membranes with DNA-Functionalized Gold Nanoparticles

One-Sun Lee and George C. Schatz

Part II: Translating Nanoscience and Technology from the Lab to the Clinic

19. Cytotoxic Assessment of Carbon Nanotube Interaction with Cell Cultures

Hanene Ali-Boucetta, Khuloud T. Al-Jamal, and Kostas Kostarelos

20. Nanoparticle Toxicology: Measurements of Pulmonary Hazard Effects Following Exposures to Nanoparticles

Christie M. Sayes, Kenneth L. Reed, and David B. Warheit

21. Nanoparticle Therapeutics: FDA Approval, Clinical Trials, Regulatory Pathways, and Case Study

Aaron C. Eifler and C. Shad Thaxton

22. Legislating the Laboratory?: Promotion and Precaution in a Nanomaterials Company

Robin Phelps and Erik Fisher

23. Navigating the Patent Landscapes for Nanotechnology: English Gardens or Tangled Grounds?

Douglas J. Sylvester and Diana M. Bowman

24. Scientific Entrepreneurship in the Materials and Life Science Industries

Jose Amado Dinglasan, Darren J. Anderson, and Keith Thomas

25. Applying the Marketing Mix (5 P's) to Bionanotechnology

Michael S. Tomczyk

26. Managing the "Known Unknowns": Theranostic Cancer Nanomedicine and Informed Consent

Fabrice Jotterand and Archie A. Alexander