Insect Cell Cultures: Fundamental and Applied Aspects

Preface. Development and characterization of insect cell lines; D. Lynn. New approaches to insect tissue culture; D. Baines. Transgenic insect cells: mosquito cell mutants and the dihydrofolate reductase gene; A.M. Fallon. Insect cell physiology; R. Bhatia. Insect cell cultivation: growth and kinetics; G. Schmid. Medium design for insect cell culture; E.-J. Schlaeger. Baculovirus-insect interactions; G.W. Blissard. Replication patterns and cytopathology of cells infected with baculoviruses; G.V. Williams, P. Faulkner. Construction of baculovirus recombinants; P.A. Kitts. Passage effect of virus infection in insect cells; P.J. Krell. Post-translational modifications in insect cells; H.-D. Klenk. Productivity of insect cells for recombinant proteins; J.E. Maruniak. Chaperone and foldase coexpression in the baculovirus-insect cell expression system; M.J. Betenbaugh, et al. Shear sensitivity of insect cells; J.J. Chalmers. Insect cell bioreactors; S.N. Agathos. Perfusion for the production of recombinant proteins in insect cells; V. Jäger. Immobilization of insect cells; Jian-Yong Wu, M.F.A. Goosen. Modelling baculovirus infection of insect cells in culture; J.F. Power, L.K. Nielsen. Scale up aspects of sparged insect-cell bioreactors; J. Tramper, et al. Oxygen gradients in small and big sparged insect-cell bioreactors; J. Tramper, et al. Downstream processing of insect cell cultures; A.R. Bernard, et al. Parvovirus diagnostics and vaccine production in insect cells; J.I. Casal. Classical swine fever virus diagnostic and vaccine production in insect cells; M.M. Hulst, R.J.M. Moormann. Production of multidomain complement glycoproteins in insect cells; P. Závodski, S. Cseh. Economicsof baculovirus&endash;insect cell production systems; D.J. Rhodes. Safety aspects of insect cell culture; G. Stacey. Regulatory issues in the use of insect-cell culture; F.L.J. van Lier. Keyword index.