The Primary Structure of Transfer RNA

Abbreviations.- 1 Transfer RNAs as Objects of Structural Research.- 2 Methods of Studying the Primary Structure of Transfer RNA.- Methods of Isolating Specimens of Individual RNAs.- Terminal Analysis.- The Stepwise-Degradation Method.- The Unit Method.- The Use of Chemical Modifications.- Fractionation of Oligonucleotides.- Spectrophotometry of Oligonucleotides.- Analysis of Oligonucleotides.- 3 The Primary Structure of Individual Transfer RNAs.- The Development of Research into the Primary Structure of tRNA Alanine tRNA from Bakers' Yeast.- Serine tRNA from Brewers' Yeast.- Tyrosine tRNA from Bakers' Yeast.- Phenylalanine tRNA from Bakers' Yeast.- Valine tRNA from Bakers' Yeast.- Subsequent Development of Structural Research.- The Primary Structure of Individual tRNAs.- Alanine tRNA from Bakers' Yeast.- Serine tRNA from Brewers' Yeast.- Tyrosine tRNA from Bakers' Yeast.- Phenylalanine tRNA from Bakers' Yeast.- Valine tRNA from Bakers' Yeast.- Tyrosine tRNA from E. coli.- AT-Formylmethionine tRNA from E. coli.- Methionine tRNA from E. coli.- Valine tRNA from E. coli.- Phenylalanine tRNA from E. coli.- Valine tRNA from T. utilis.- Isoleucine tRNA from T. utilis.- Tyrosine tRNA from T. utilis.- Serine tRNA from Rat Liver.- Phenylalanine tRNA from Wheat Germ.- Aspartate tRNA from Brewers' Yeast.- Tryptophan tRNA from E. coli.- Leucine tRNA from E. coli B.- "Denaturable" Leucine tRNA from Bakers' Yeast.- Valine tRNA2 from E. coli.- Glutamine tRNAi and tRNAn from E. coli.- Glycine tRNA from E. coli.- Common Features and Differences in Structure of Individual tRNAs.- Structure of the Isoacceptor tRNAs.- Species Differences between Individual RNAs.- 4 Minor Components of tRNA.- The Origin of the Minor Components.- The Role of the Minor Components.- Adenosine Derivatives.- Inosine.- Derivatives of Guanosine.- Uridine Derivatives.- Pseudouridine.- Dihydrouridine.- Other Uridine Derivatives.- Cytidine Derivatives.- Thiopyrimidines.- 2'-O-Methylribosides.- Unidentified Minor Components.- Conclusion.