Life Extension: Lessons from Drosophila

Preface
Alexander M. Vaiserman, Alexey A. Moskalev, Elena G. Pasyukova

SECTION I: Genetic Regulation of Longevity

CHAPTER 1. Neuronal Genes and Developmental Neuronal Pathways in Drosophila Lifespan Control
Elena Pasyukova, Alexander Symonenko, Natalia Roshina, Mikhail Trostnikov, Ekaterina Veselkina, Olga Rybina

CHAPTER 2. Gadd45 Proteins in Aging and Longevity of Mammals and Drosophila
Alexey A. Moskalev, Ekaterina N. Plyusnina and Mikhail V. Shaposhnikov

CHAPTER 3. Superoxide Dismutase (SOD) Genes and Aging in Drosophila
John Tower

CHAPTER 4. Effect of Wolbachia Infection on Aging and Longevity-Associated Genes in Drosophila
Oleksandr M. Maistrenko, Svitlana V. Serga, Alexander M. Vaiserman and Iryna A. Kozeretska

SECTION II: Drosophila Models for Aging-Associated Diseases

CHAPTER 5. Skeletal muscle homeostasis and aging in Drosophila
Melissa J. Puppa and Fabio Demontis

CHAPTER 6. Drosophila Models of Cardiac Aging and Disease
Alyson Sujkowski, Chelsea Richardson and Robert Wessells

CHAPTER 7. Parallels between Mammals and Flies in Inflammatory Bowel Disease
Theodoulakis Christofi and Yiorgos Apidianakis

CHAPTER 8. Protein Quality Control in Brain Aging: Lessons from Protein Misfolding Disorders in Drosophila
Lorena de Mena, Pedro Fernandez-Funez and Diego E. Rincon-Limas

CHAPTER 9. Drosophila Models in Therapeutic Drug Discovery Related to Aging
Charles Nichols

SECTION III: Life-Extending Treatments

CHAPTER 10. Life-Extending Effect of Phytochemicals in Drosophila
Lee Shin-Hae and Min Kyung-Jin

CHAPTER 11. Life Extension in Drosophila by Histone Deacetylase Inhibitors
Alexander M. Vaiserman and Elena G. Pasyukova

CHAPTER 12. An Evolutionary Analysis of Healthspan Extension Using Diet: Have We Come to the End of the Ponce de Leon Trail?
Grant A. Rutledge and Michael R. Rose

CHAPTER 13. Atmosphere, Metabolism and Longevity
Khatchik Muradian

CHAPTER 14. Effects of Mild Stresses Applied in Adults on Aging and Longevity
Éric Le Bourg

CHAPTER 15. Strategies for Stage-Specific Extension of Longevity
Robert Arking

Index