Chemical Synthesis: Gnosis to Prognosis

Preface. Asymmetric Synthesis: I - Fundamentals and Recent Advances. II - Some Aspects of Asymmetric Catalysis with Transition-Metal Complexes; H.B. Kagan. Addition of Enolates and Metalloalkyls to Imines. Stereospecific Synthesis of beta-Lactams, Amines, Aziridines and Aminols; G. Cainelli, et al. Target-Driven Organic Synthesis: Reflections on the Past, Prospects for the Future; S. Hanessian. Optically Active Transition Metal Compounds Containing Chiral Transition Metal Atoms; H. Brunner. Biomimetic Chemistry. Bifunctional Binding and Catalysis; R. Breslow. Design of Enzyme Inhibitors. Answering Biological Questions Through Organic Synthesis; P.A. Bartless. Enantioselective Catalysis with Transition Metal Complexes; H. Brunner. Directed Aromatic Metalation: A Continuing Education in Flatland Chemistry; V. Snieckus. Panel Discussion I. As We Head Into the 21st Century, is There Still Value in Total Synthesis of Natural Products as a Research Endeavor? C.H. Heathcock. Convergent Strategies for Synthetic Receptors; P. Timmerman, et al. The Advancement of Radical-Based Synthetic Strategies: From Reagent Design to Polymer Modification; C. Chatgilialoglu. Templated Synthesis of Enzyme Mimics: How Far Can We Go? S. Anderson, J.K.M. Sanders. Towards a Chemical Etiology of the Natural Nucleic Acids' Structure; A. Eschenmoser. Principles of Antibody Catalysis; D. Hilvert. New Homocalixarenes and Catenanes: From Molecular Recognition to Mechanical Bonds; S. Meier, et al. Self-Assembly in Chemical Synthesis; S.J. Langford, J.F. Stoddart. Oligonucleotide-Directed Recognition of Double-Helical DNA; C. Hélène, T. Garestier. Can Enzyme Mimics Compete With Catalytic Antibodies? C.J. Walter, et al. Panel Discussion II. Synthesis of Giant Modular Structures: SupramolecularAssemblies and Well-Defined Macro-Molecules; J. Michl. Polymer Synthesis and Stereochemistry with Transition Metal Catalysts; R. Waymouth, et al. Making Unnatural Products by Natural Means; S.J. Langford, J.F. Stoddart. Supramolecular Chemistry and Chemical Synthesis. From Molecular Interactions to Self-Assembly; J.-M. Lehn. Synthetic Approaches to Functional Polymers; F. Ciardelli, et al. Transduction of Molecular Interactions into Macroscopic Properties; H.C. Visser, et al. Approaches to Synthesis Based on Non-Covalent Bonds; G.M. Whitesides, et al. Panel Discussion III. Organic Synthesis and the Life Sciences; D. Arigoni. Index.