Molecular Diversity in Drug Design

Contributors. Acknowledgements. Preface. Issues in Molecular Diversity and the Role of Ligand Binding Sites; J. Smith, et al. Molecular Diversity in Drug Design. Application to High-Speed Synthesis and High-Throughput Screening; C.G. Newton. Background Theory of Molecular Diversity; V.J. Gillet. Absolute vs Relative Similarity and Diversity; J.S. Mason. Diversity in Very Large Libraries; L. Weber, M. Almstetter. Subset-Selection Methods For Chemical Databases; P. Willett. Molecular Diversity in Site-focused Libraries; D.C. Roe. Managing Combinatorial Chemistry Information; K. Davies, C. White. Design of Small Libraries for Lead Exploration; P.M. Andersson, et al. The Design of Small- and Medium-sized Focused Combinatorial Libraries; R.C. Lewis. Index.