Guide to the NMR Empirical Method: A Workbook

Section 1 General considerations, appearance of a good spectrum, concept of the chemical shift, use of the integration curve, and D2O exchange.- Section 2 First-order spin systems, presence of impurities, and an unknown.- Section 3 General problems involving chemical shifts, first-order spin systems, exchange rates, and use of the integration curve.- Section 4 First-order couplings to H2, C13, F19, and P31; spinning side bands.- Section 5 Simple unexpected nonequivalence of protons.- Section 6 Higher-order spin systems; AB, AB2, A2B2, A?2B?2, ABX, and ABC; calculations for AB, AB2, and ABX; "virtual" coupling.- Section 7 General problems involving higher-order patterns..- Section 8 Unexpected nonequivalence of protons involving higher-order spin systems.- Section 9 General problems.- Answers.- Appendix A Characteristic positions of various proton signals at 60 Mcps with reference to internal tetramethylsilane.- Appendix B Shoolery's additive constants.- Appendix C Major factors which affect the magnitude of coupling constants.- Appendices D, E, and F General note.- Spin-spin coupling constants for protons on saturated systems.- Spin-spin coupling constants for aldehydic protons and protons on multiple bonds.- Spin-spin coupling constants for protons on aromatic systems.- Molecular Formula Index.