The Immune Response to Implanted Materials and Devices: The Impact of the Immune System on the Succe

Host response to implanted materials and devices - overview.- Innate and acquired immunity: umoral and cellular components (Protein adsorption, cell recruitment, tissue response).- Acute/Chronic inflammation, foreign body reaction - implications.- Macrophages: from immune response to tissue restoration.- Host response to cell-grafted biomaterials.- Host response to therapeutic nanoparticles.- Host response to synthetic versus natural biomaterials (The effects of the composition, structure on function, stability, and final outcome).- Biomimicry at the cell-material interface to mitigate the immune reaction.- Bioactive materials design for immunomodulation - exploiting the patient's own body machinery to achieve functional tissue restoration.- Host response to materials for orthopaedic applications: current approaches and future perspectives.- Methods to activate cellular immunity or determine immune evasion.