Management of Knowledge-Intensive Organizations: Governance Models for Transformative Discovery

Chapter 1 INTRODUCTION

1.      Management of Knowledge- Intensive Organizations

Theoretical Framework

2. Academic Knowledge Production and KIOs

            Two Research Streams

Knowledge Production Systems in Academic Sciences

Concerns over Academic Knowledge Production

Governance of Academic Knowledge Production

3. Governance Models of Knowledge Intensive Organizations

Relations with Neighboring Fields

Governance Models in Management Theories of KIOs

4.  Organization of Chapters

PART I

Chapter 2 TRANSLATIONAL SCIENCE AND BOUNDARY

                CONCEPTUALIZATION

1.                               Translational Science and KIO Framework

Components of Translational Science

Consistencies with KIO Framework

2.      Boundaries and Governance

Knowledge Integration and Boundaries

Application to Translational Science

The Need of the Academic-Specific Boundary Conceptualization

3.      Framework of KIOs, Boundaries, and Buffer

Threshold Elements of Boundary Spanning

            Modalities of Governance

4.      Conclusion

Chapter 3 TRUSTEESHIP GOVERNANCE AND CHALLENGES TO SCIENTIFIC

                 KNOWLEDGE-INTENSIVE-ORGANIZATIONS

1.      Introduction

2.      Captures, Goal Replacement, Non-academic legitimacies

Captures

Academic Captures

Goal Replacement

Measures to Identify Captures

3.      Governance Models

Governance Models of Academic KIOs

Directions of Enhancing Models

4.      Conclusion

Part II

Chapter 4 INSTITUTIONAL BARRIERS AND GOVERNANCE

1.      Introduction

2.      Barriers to Institutional Validation

Informed Consent as a Buffer

Fair Transaction Model of Consent

            Measurement of Preconditions

3.      Fairness-Based Stakeholder Theory in Translational Science

Fairness-Based Stakeholder Theory and Informed Consent

Implementation Mechanism

4.      Conclusion

Chapter 5 RESEARCH POLICY AND KNOWLEDGE-INTENSIVE-ORGANIZATION

2.      Research Policies and Bioethics

Competing Factors in Research Policies

Transnational Efforts vs. State-Centric Effort

Institutional Approach

Moral Stakeholders and Civic Epistemology

3.      Discovery Pathways

Basic Research in the US and German KIOs

Translational Pathways in the US and German KIOs

4.      Conclusions

Chapter 6 NEW GOVERNANCE MODELS FOR DISCOVERIES OF VACCINE  

1.      Introduction

2.      Research Alliances of Multilateral KIOs

     Private-Public Partnerships in Management Theories

     Buffers for Autonomy of KIOs

                 Governance in Management Theories

3.      Application to Vaccine Research

      Background: MDR-TB Initiative

      Problems in Governance

4. Governance Model for Vaccine Discoveries

     Vaccine Science and Alliance Governance of KIOs

5.      Conclusion

Part III

Chapter 7 SCIENCE AND INSIGHTS FROM THE HUMANISTIC DISCIPLINES

1.      Introduction

2.      Intellectual Property Policies of Biomedical Consortia

Proprietary Knowledge in Scientific Commons

Intellectual Property Policies as Governance Mechanisms

      Governance Theories and Property Rights

3.      Self-Regulation of Science and Moral Identity

                 Integration towards Innovation Pathways

     Bridging Mechanisms for Governance

     Reaching to Common Ground with the Agency-based Governance

      4. Conclusion

Chapter 8 CONCLUSION

2.      Self-regulation and Trusteeship Governance

Directions of Extension: Agency-perspective Governance

Directions of Extension: Stakeholder-perspective Governance

3.      Intellectual Property Policies as Governance Mechanisms

Imposing Ownership Requirements

            Unbundling of Rights

4.      Conclusion

Theoretical and Practical Implications

Limits and Future Studies