Hybrid Systems Biology: 6th International Workshop, HSB 2019, Prague, Czech Republic, April 6-7, 201

A multimodular system to study the impact of a focal lesion in neuronal cell cultures.- Reachability analysis and hybrid systems biology - In Memoriam Oded Maler.- Reaction networks, oscillatory motifs and parameter estimation in biochemical systems.- Fixed-point computation of equilibria in biochemical regulatory networks.- Rejection-based simulation of stochastic spreading processes on complex networks.- Controlling noisy expression through auto regulation of burst frequency and protein stability.- Extracting landscape features from single particle trajectories.- A hybrid HMM approach for the dynamics of DNA methylation.- Using a hybrid approach to model central carbon metabolism across the cell cycle.- Data-informed parameter synthesis for population Markov chains-. rPrism - A software for reactive weighted state transition models.- Hybrid modeling of metabolic-regulatory networks.